scienceitНаука. Инновации. ТехнологииScience. Innovations. Technologies2308-4758North-Caucasus Federal Universityscienceit-275Research ArticleБИОЛОГИЧЕСКИЕ НАУКИBIOLOGICAL SCIENCESБЕЛОК-ПОЛИСАХАРИДНЫЕ МИКРОКАПСУЛЫ, СФОРМИРОВАННЫЕ НА МАТРИЦАХ РАЗЛИЧНОЙ ПРИРОДЫProtein-polysaccharide microcapsules formed on matrices of different structuresСупрунчукВиктория ЕвгеневнаSuprunchukViktoria Evgen'evnavikasuprunchuk@gmail.comДенисоваЕвгения ВладимировнаDenisovaEvgenija Vladimirovnaden_ev@mail.ruСеверо-Кавказский федеральный университетРоссияNorth-Caucasus Federal UniversityRussian Federation20170509202202199206Copyright © Супрунчук В.Е., Денисова Е.В., 20222022Супрунчук В.Е., Денисова Е.В.Suprunchuk V.E., Denisova E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://scienceit.elpub.ru/jour/article/view/275

В данной работе рассматривается возможность формирования микрокапсул путем послойной адсорбции биополиэлектролитов на ядрах неорганической (частицы СаСО3) и полимерной природы (полистирольные частицы). Нами была осуществлена оценка размеров полученных микрокапсул, их форма, количественный выход. В качестве высокомолекулярного полианиона был использован фукоидан (F), в качестве высокомолекулярного поликатиона - бычий сывороточный альбумин (БСА). Удаление ядер осуществлялось путем понижения рН системы до 4, в случае карбонатной матрицы, или вымыванием с помощью тетрагидрофурана, в случае полистирольных носителей. Установлено, что природа матрицы, используемой для формирования микрокапсул, влияет на степень включения белка и выход полиэлектролитных частиц.

In this paper we consider the possibility of forming microcapsules by layer-by-layer adsorption of polymers on inorganic cores and polymeric nature. Removal of the carbonate cores were performed by lowering the pH of the system to 4.5. Removal of the polypropylene matrix were carried out using tetrahydrofuran in the case of polystyrene media. It is established that the nature of the matrix used for the formation of microcapsules, affect the degree of incorporation of protein and the yield of polyelectrolyte particles.

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The authors declare that there are no conflicts of interest present.