FEATURES MORPHOLOGY ABNORMAL FORMS OF ERYTHROCYTES BY ATOMIC FORCE MICROSCOPY

Abstract

Annotation The possibility of using atomic force microscopy (AFM) to qualitatively assess the morphology and the visualization of abnormal forms of red blood cells (RBCs), in comparison with traditional methods of optical microscopy, was studied in this article. The analysis of sample preparation methods of another authors showed what kind of methods are better and more useful. Based on that analysis, the authors chose optimal method without significant effect on morphological features of cells. The authors identified abnormal forms of the red blood cells under heavy metals salts effect. It was established that atomic force microscopy is an important tool for visualization the morphology of abnormal forms of red blood cells. The authors concluded that usage of software tools (Nova PX) provides researches by complete pictures of the dimensional characteristics and parameters of red blood cells.